Insights into the Roles of B Cells in Patients with Sepsis

Insights into the Roles of B Cells in Patients with Sepsis

Blog Article

Sepsis is a life-threatening yet common disease, still posing high mortality worldwide.Sepsis-related deaths primarily occur during immunosuppression; the disease can hamper the numbers and function of B cells, which mediate innate and adaptive immune responses to maintain immune homeostasis.Dysfunction of B cells, along peoria orange barrels with aggravated immunosuppression, are closely related to poor prognosis.However, B cells in patients with sepsis have 1307 rough country garnered little attention.

This article focuses on the significance of B-cell subsets, including regulatory B cells, in sepsis and how the counts and function of circulating B cells are affected in patients with sepsis.Finally, potential B-cell-related immunotherapies for sepsis are explored.